Table 1. Genes previously associated with learning and memory with transcript isoforms that differ significantly in abundance between naïve and trained males 24 hr after training.
| Flybase | Gene | Transcript | Fold Differencea | FDR q Value |
|---|---|---|---|---|
| FBgn0000479 | dunce | FBtr0070522 | Only in traineda | 1.05E-09 |
| FBgn0038934 | Gld2 | FBtr0084200 | Only in traineda | 3.19E-05 |
| FBgn0261854 | aPKC | FBtr0303436 | 3.34 up | 1.63E-03 |
| FBgn0023479 | tequila | FBtr0076528 | 3.32 up | 7.08E-28 |
| FBgn0028734 | Fmr1 | FBtr0301386 | 2.99 up | 1.07E-08 |
| FBgn0004648 | silver | FBtr0070085 | 2.79 up | 1.30E-13 |
| FBgn0003520 | staufen | FBtr0301614 | 2.28 up | 1.72E-09 |
| FBgn0003396 | schnurri | FBtr0088099 | 2.19 up | 1.35E-09 |
| FBgn0041111 | lilliputian | FBtr0290041 | 2.10 up | 8.00E-03 |
| FBgn0035938 | orb2 | FBtr0076561 | 1.81 up | 5.00E-04 |
| FBgn0038975 | Nrx-1 | FBtr0301485 | 1.71 up | 7.63E-21 |
| FBgn0003380 | Sh | FBtr0303902 | 1.64 up | 2.00E-03 |
| FBgn0000054 | Adf1 | FBtr0086113 | 1.64 up | 1.00E-02 |
| FBgn0259243 | Pka-R1 | FBtr0299891 | 1.59 up | 3.30E-02 |
| FBgn0030412 | tomosyn | FBtr0073678 | 1.59 up | 8.65E-07 |
| FBgn0250753 | exba | FBtr0078747 | 1.49 up | 1.00E-02 |
| FBgn0004648 | silver | FBtr0070087 | 1.36 up | 4.00E-03 |
| FBgn0259246 | brp | FBtr0299916 | 1.33 up | 2.00E-03 |
| FBgn0259246 | brp | FBtr0299915 | 1.30 up | 6.00E-03 |
| FBgn0016917 | Stat92E | Fbtr0100457 | 1.30 up | 2.00E-02 |
| FBgn0030412 | tomosyn | FBtr0300376 | 1.29 up | 2.00E-02 |
| FBgn0004624 | CamKII | FBtr0100146 | 1.28 up | 3.00E-03 |
| FBgn0000536 | eas | FBtr0074212 | 1.17 up | 2.00E-02 |
| FBgn0086902 | kis | FBtr0078144 | 1.09 up | 3.00E-02 |
| FBgn0003501 | Src64b | FBtr0100504 | 11.38 down | 2.59E-06 |
| FBgn0030412 | tomosyn | FBtr0073676 | 7.73 down | 5.14E-14 |
| FBgn0000536 | eas | FBtr0074213 | 2.86 down | 3.03E-05 |
| FBgn0035938 | orb2 | FBtr0076564 | 2.65 down | 2.00E-03 |
| FBgn0004624 | CamKII | FBtr0100148 | 2.31 down | 2.16E-08 |
| FBgn0038975 | Nrx-1 | FBtr0084256 | 2.20 down | 5.80E-25 |
| FBgn0259243 | Pka-R1 | FBtr0302639 | 2.07 down | 2.70E-08 |
| FBgn0000422 | Ddc | FBtr0081166 | 1.89 down | 1.00E-03 |
| FBgn0000054 | Adf1 | Fbtr0086112 | 1.89 down | 3.00E-03 |
| FBgn0259246 | brp | Fbtr0300542 | 1.65 down | 6.23E-05 |
| FBgn0035938 | orb2 | FBtr0076562 | 1.46 down | 3.00E-02 |
| FBgn0016917 | Stat92E | Fbtr0089487 | 1.41 down | 4.00E-03 |
| FBgn0004648 | silver | FBtr0290017 | 1.40 down | 5.00E-03 |
| FBgn0028734 | Fmr1 | FBtr0082198 | 1.40 down | 1.00E-03 |
| FBgn0003396 | schnurri | FBtr0088101 | 1.39 down | 3.00E-03 |
| FBgn0003392 | Shi | FBtr0074123 | 1.36 down | 1.00E-03 |
| FBgn0004648 | silver | FBtr0070086 | 1.31 down | 6.14E-07 |
| FBgn0003371 | sgg | FBtr0070467 | 1.28 down | 2.00E-03 |
| FBgn0037913 | fabp | FBtr0100321 | 1.10 down | 2.00E-03 |
| FBgn0013334 | Sap47 | FBtr0301655 | 1.10 down | 3.00E-02 |
Columns include: Flybase identification (Flybase), gene symbol (Gene), transcript identification (Transcript), fold difference, and FDR q value. FDR, false discovery rate.
a
“Only in trained” indicates that these transcript isoforms had sequence reads that were only detected in trained males and not in naïve males; “up” and “down” indicate transcripts that are either up-regulated or down-regulated in trained flies, respectively.