Table 5.
AUC0→12 h (μg h/mL) | Cmax (μg/mL) | Tmax (h) | |
---|---|---|---|
Raw fenofibrate | 144.46 ± 61.57 | 20.52 ± 8.34 | 3 ± 0.82 |
Commercial product | 635.68 ± 98.14 | 89.60 ± 12.02 | 2.63 ± 0.75 |
Prepared powder (SC3) | 667.90 ± 106.29 | 92.88 ± 7.05 | 3 ± 0 |
Note: Data are expressed as mean ± standard deviation (n = 5).
Abbreviations: AUC, area under the curve; Cmax, maximal serum concentration; SC3, supercritical method 3 (fenofibrate:Neusilin UFL2 = 40:60); Tmax, time to peak concentration.