Table 2.

Case definitions of syphilis cases from included studies

Country	Case definition
Albania [9]	Diagnosis of syphilis during time period leading to inclusion in national surveillance data.
Belarus [4]	From review paper, case definition given only as cases of syphilis per 100 000 population.
Bulgaria [6]	Diagnosis of syphilis during time period leading to inclusion in national and then EU surveillance data
Czech [6]	Diagnosis of syphilis during time period leading to inclusion in national and then EU surveillance data
Estonia [6]	Diagnosis of syphilis during time period leading to inclusion in national and then EU surveillance data.
Hungary [10]	Clinician diagnosis via direct detection of pathogens, results of serological tests and clinical picture.
Latvia [6]	Diagnosis of syphilis during time period leading to inclusion in national and then EU surveillance data
Lithuania [6]	Diagnosis of syphilis during time period leading to inclusion in national and then EU surveillance data
Poland [11]	Case reports referred to Public Health department.
Romania [8]	Cases detected from national screening procedures.
Slovakia [6]	Diagnosis of syphilis during time period leading to inclusion in national and then EU surveillance data
Slovenia [6]	Diagnosis of syphilis during time period leading to inclusion in national and then EU surveillance data
Turkey [5]	Diagnosis of syphilis during time period leading to inclusion in national surveillance data.