FIG. 3.

Evaluation of antibody responses to overlapping peptides of V2 by peptide microarray analysis. Microarray peptide analysis was done using plasma from 80 HIV-1-uninfected vaccine recipients and 20 placebo recipients (set A). (A) Reactivity of plasma with peptides from seven HIV-1 Group M subtypes (M consensus, A, B, C, D, CRF01, and CRF02). (B) Overall reactivity of RV144 plasma samples to the V2 loop. Peptide positions are shown on the x-axis and percent responses are shown on the y-axis. The peptide positions are aligned with the amino acid sequence of HXB2 protein and the sequence of 92TH023 V2 loop is shown for comparison.