Table 3.
Statistics on Vaginally Challenged Animals
| Gel | Gel dosing relative to challenge | Infected/challenged | Protection vs. CG | p value vs. CG |
|---|---|---|---|---|
| MIV-150/ZA/CG | 24 h pre (±1 h post) | 1/14 | 89% | <0.002 |
| MIV-150/ZA/CG | 1 h post | 3/7 | 29% | <0.7 |
| ZA/CG | 8 h pre | 2/6 | 48% | <0.37 |
| ZA/CG | 24 h pre | 4/8 | 22% | <0.7 |
| ZA/CG | 1 h post | 5/6 | 0% | 1 |
| CG | 16/25a |
The number of challenged animals for CG included 9 real time (Table 1)and 16 historical controls.