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. 2012 Jun 26;5(6):812–822. doi: 10.1242/dmm.009910

Fig. 7.

Fig. 7.

Structure of the rat dmbo critical region. (A) Genetic linkage map (left) and physical map (right) of the region of rat chromosome 14 encompassing the dmbo allele. The linkage map was derived from examination of 614 progeny of a (BN/SsNSlc × KFRS4/Kyo)F1 × KFRS4/Kyo backcross. Recombination events between the markers Ablim2_SNP(H42Y) and Hmx1_SNP(L251L) place the dmbo allele critical region within a 410-kb interval. Resequencing data revealed a novel 5777-bp deletion between the Cpz and Hmx1 genes (red). (B) Structure of the KFRS4/Kyo deletion breakpoint.