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. 2012 May 31;5(6):823–833. doi: 10.1242/dmm.008557

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© 2012. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

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Fig. 1. — IL-1α is expressed by microglia/macrophages early after experimental SAH. Panels show coronal brain sections of SAH animals 12 hours after bleed. Images are representative of the cortex, striatum and adjacent area to the bleed site after SAH. IL-1α-positive fluorescent cells (red); Iba1-positive fluorescent cells show microglia/macrophages (green). Images are merged to reveal IL-1α colocalisation with microglia/macrophages. Graph shows the percentage of IL-1α-positive microglia cells adjacent to the bleed site (n=5). No IL-1α-positive cells were seen in sham controls. Coronal inserts indicate the area that the image was taken from and insert shows high magnification of IL-1α/Iba1 colocalisation. Scale bars: 50 μm.