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. 2012 Oct 26;7:5529–5543. doi: 10.2147/IJN.S36071

Figure 5.

Figure 5

(A and B) Long-term stability results for BSA in the NEDDS. (A) Primary structural integrity changes in BSA in the NEDDS when stored at room temperature for 180 days. Lane 1, BSA aqueous solution; lane 2, BSA NEDDS stored at room temperature for 30 days; lane 3, BSA NEDDS stored at room temperature for 60 days; lane 4, BSA NEDDS stored at room temperature for 90 days; lane 5, BSA NEDDS stored at room temperature for 180 days; lane 6, BSA aqueous solution stored at room temperature for 30 days; lane 7, BSA aqueous solution stored at room temperature for 60 days; lane 8, BSA aqueous solution placed at room temperature for 90 days; lane 9, BSA aqueous solution stored at room temperature for 180 days; lane 10, prestained protein ladder. (B) Relative content and bioactivity of the BSA in the nanoemulsion delivery system stored at room temperature for 180 days.

Note: No obvious changes in relative content and bioactivity were observed between the fresh samples and BSA NEDDS stored at room temperature for 30, 90, and 180 days. Abbreviations: BSA, bovine serum albumin; NEDDS, nanoemulsion drug-delivery system.