Table 4.
Pooled Estimates and Heterogeneity Values of the Mean PDQ-39 SI and Mean Values for Each Dimension
| HRQOL | Pooled estimate of mean values (95% CI) |
Test of heterogeneity |
|
|---|---|---|---|
| χ2 test, p-value | I2 test, % | ||
| PDQ-39 SI (all studies) | 34.0 (31.0–37.1) | <0.001 | 97 |
| PDQ-39 SI (by regions) | |||
| North America | 28.1 (23.3–39.9) | 0.14 | 54 |
| South America | 40.9 (38.1–43.7) | <0.001 | 81 |
| Western Europe | 31.7 (27.6–35.8) | <0.001 | 95 |
| Eastern Europe | 46.7 (33.4–60.0) | <0.001 | 99 |
| Asia–Pacific | 29.2 (25.5–32.8) | <0.001 | 95 |
| Dimensions of PDQ-39 (all studies) | |||
| Mobility | 43.1 (39.3–47.0) | <0.001 | 96 |
| Activities of daily living | 40.3 (36.2–44.3) | <0.001 | 96 |
| Emotional well-being | 36.7 (32.3–41.1) | <0.001 | 98 |
| Stigma | 32.0 (27.5–36.6) | <0.001 | 97 |
| Social support | 21.6 (17.6–25.7) | <0.001 | 97 |
| Cognition | 34.2 (30.8–37.5) | <0.001 | 96 |
| Communication | 29.9 (26.9–32.9) | <0.001 | 95 |
| Bodily discomfort | 41.5 (37.4–45.5) | <0.001 | 97 |
HRQOL=health-related quality of life; PDQ-39=Parkinson's Disease Questionnaire; SI=summary index.