Table 1. Self-assembling QD-scFv complexes and their anti-tumor specifities.
No | Complex composition | Complex specificity | Cell staining | |||
Targeting module | Visualizing module | SKOV-3 (HER2/neu-overexpressed) | A431 (HER1-overexpressed) | CHO(control) | ||
1 | (4D5scFv)2-Bn | QD605-Bs | HER2/neu | + | - | - |
2 | QD565-Bs | HER2/neu | + | - | - | |
4 | 425scFv-Bs | QD605-Bn | HER1 | - | + | - |
5 | QD565-Bn | HER1 | - | + | - |