| AP2alpha |
+ |
− |
cranial neural crest and limb mesenchyme development [80], [81]
|
| CdxA |
+ |
− |
pattering of the anteroposterior axis [117]
|
| Churchill |
+ |
+ |
mediator of FGF signaling during neural development [68]
|
| CTCF |
+ |
− |
insulator activity [118]
|
| EBF1 |
− |
+ |
B-cell differentiation [70]
|
| ESR1 |
− |
+ |
development and maintenance of normal sexual and reproductive function [119]
|
| c-ETS |
− |
+ |
embryonic and hematopoietic development; angiogenesis [83]
|
| GATA-3 |
− |
+ |
expressed in T cells in adult animals; expression in non-hematopoietic tissues/organs during embryogenesis [120]
|
| Inr |
− |
+ |
RNA polymerase II transcription initiation [121]
|
| INSM1 |
+ |
+ |
neuroendocrine differentiation [69]
|
| IRF1/IRF2 |
+ |
− |
development and activation of immune cells; IRF2 suppresses transcriptional activity of IRF-1 [122]
|
| Klf4 |
+ |
− |
development; differentiation; maintenance of tissue homeostasis [123]
|
| MZF1 1–4 (domain 1) |
+ |
+ |
hemopoietic development; differentiation of myeloid cells [72], [73], [74]
|
| MZF1 5–13 (domain 2) |
+ |
− |
|
| NR3C1 |
− |
+ |
inflammatory response; cellular proliferation; differentiation in target tissues through interaction with steroidal hormones (Glucocorticoids) [124]
|
| Pax2 |
− |
+ |
kidney development; establishing mid-hindbrain border [71]
|
| Pax4 |
+ |
+ |
organogenesis of the pancreas [71]
|
| Pax5 |
+ |
+ |
B-cell differentiation; neural development [71]
|
| PPARG:: RXRA |
− |
+ |
adipocyte differentiation; lipogenesis [125]
|
| REST |
+ |
− |
repression of neuronal genes in stem cells and non-neuronal tissues [126]
|
| RREB1 |
− |
+ |
ubiquitously expressed repressor [79], [127]
|
| RXR::RAR_DR5 |
+ |
− |
embryonic development; tissue homeostasis; cell proliferation; differentiation; apoptosis [128]
|
| Sox2 |
− |
+ |
progression of neurogenesis; maintenance of neurons [129]
|
| Sp1 |
+ |
− |
trans-activator; ubiquitously expressed [61]
|
| SPI-1 (PU.1) |
− |
+ |
differentiation of myeloid cells, B-cells, macrophages [130]
|
| Tal1:GATA-1 |
+ |
− |
erythroid differentiation [82]
|
| Tcfcp2l1 |
+ |
− |
transcriptional repressor [131], [132]
|
| Zfx |
+ |
− |
self-renewal and maintenance of embryonic and hematopoietic stem cells [133]
|
| znf143 |
− |
+ |
trans-activation of small nuclear RNA (snRNA) and snRNA-type promoters [134]
|
