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. 2012 Oct 25;7(10):e47998. doi: 10.1371/journal.pone.0047998

Figure 2. Expression of HOTAIR and EZH2 in primary versus metastatic carcinoma.

Figure 2

Primary breast carcinomas with their matched metastases are stained with an RNA in situ hybridization probe for HOTAIR (rows 1 and 2) or immunohistochemical antibody for EZH2 (rows 3 and 4). Expression levels are indicated as negative (−), weakly positive (+), and strongly positive (++). As depicted, some metastatic carcinomas have increased expression compared to their matched primary carcinomas, while some metastatic carcinomas have decreased expression compared to their matched primary carcinomas.