Figure 5. BDNF mRNA expression in the P5 and P8 rat hippocampus.
(A) Autoradiographic images demonstrate expression of BDNF mRNA in the P5 male and female hippocampus following Control or CNN treatment. (B) Darkfield images from a male Control-treated P5 rat showing expression patterns of BDNF in CA1 (a) CA3 (b) and DG (c). (C) Quantification of hybridization intensities from P5 male and female Control- and CNN-treated pups in CA1, CA3 and DG. n=4 in each group. (D) Quantification of hybridization intensities from P8 male and female Control- and CNN-treated pups in CA1, CA3 and DG. n=4 in male Control, female Control and female CNN groups, and 5 in male CNN group. Data shown are ± S.E.M. Scale bars: 1 mm in A, 200 μM in B. * indicates p<0.05, ** indicates p<0.01.