Table 4.
Univariate analysis for post-RT decompressive surgery
| Characteristic | Odds ratio | 95% CI | p-value |
|---|---|---|---|
| Age* |
0.97 |
0.9 – 1.02 |
0.20 |
| Sex (F vs. M) |
0.8 |
0.3 – 2.6 |
0.71 |
| Duration of symptoms prior to RT |
|
|
|
| ≤ 6 months |
reference |
|
|
| 6 – 18 months |
0.79 |
0.3 – 2.5 |
0.69 |
| > 18 months |
1.08 |
0.3 – 4.2 |
0.92 |
| Total score at diagnosis |
|
|
|
| (≥ 6 vs. < 6) |
2.71 |
0.9 – 7.9 |
0.07 |
| Disease severity |
|
|
|
| Mild |
reference |
|
|
| Moderate |
2.78 |
0.7 – 10.6 |
0.14 |
| Severe |
3.33 |
0.4 – 25.4 |
0.25 |
| Prior surgery |
3.89 |
0.2 – 65.2 |
0.35 |
| Prior steroid use |
1.24 |
0.5 – 3.4 |
0.68 |
| Response to prior steroids |
|
|
|
| (PR vs. none) |
0.84 |
0.2 – 4 0 |
83 |
| Steroids at initiation of RT |
1.17 |
0.4 – 3.3 |
0.77 |
| Current smoking |
3.6 |
1.3 – 10.3 |
0.02# |
| Total score at 1 month |
|
|
|
| (> 4 vs. ≤ 4) |
3.03 |
1.04 – 8.9 |
0.04# |
| Total score at 4 months* |
1.65 |
1.2 – 2.3 |
0.003# |
| Symptoms at diagnosis: |
|
|
|
| Soft tissue |
0.63 |
0.2 – 1.7 |
0.37 |
| Proptosis |
1.15 |
0.4 – 3.6 |
0.81 |
| EOM dysfunction |
0.62 |
0.2 – 1.7 |
0.35 |
| Objective vision loss |
1.59 |
0.6 – 4.4 |
0.37 |
| Diplopia |
2.63 |
0.6 – 12.5 |
0.23 |
| Symptoms at 4 months: |
|
|
|
| Soft tissue |
1.22 |
0.4 – 3.5 |
0.70 |
| Proptosis |
2.12 |
0.6 – 7.1 |
0.22 |
| EOM dysfunction |
2 |
0.7 – 5.7 |
0.19 |
| Objective vision loss |
4.45 |
1.5 – 12.9 |
0.01# |
| Diplopia | 1.03 | 0.4 – 2.9 | 0.96 |
* denotes continuous variable, # denotes statistical significance.
RT = radiation therapy, CI = confidence interval, F = female, M = male,
PR = partial response, EOM = extraocular eye muscle.