Table 2.

Invariant genes (between datasets) among common leading edge and Fisher-selected genes: Wang and van de Vijver data sets - see Informative Genes section for summary citations below

Gene symbol	Full name	Summary
MAD2L1	Mitotic arrest-deficient2, S. Cerevisiae, homolog-like 1	Overexpressed in breast and ovarian cancers [31,32]
PTTG1	Pituitary tumor-transforming gene 1	Oncogene related with breast cancer [33]
BUB1B	Budding uninhibited by benzimidazoles1, S. Cerevisiae homolog of beta	Overexpressed in breast cancer [31]
SQLE	Squalene epoxidase	Overexpressed in breast cancer and significantly inversely related to distant metastasis-free survival in early stage breast cancer [34]
E2F1	E2F transcription factor 1	Related with breast cancer outcome [35]
TSTA3	Tissue specific transplantation antigen P35B	Conserved in several breast cancer subtypes [36]

For each dataset common Fisher and leading edge genes were selected, and then intersected between the two datasets. Genes previously connected to cancer (with summaries) are listed here, and remaining genes are included in (Additional file 1: Table S1).