Table 2.
hTERC amplification measured by FISH in exfoliated cervical epithelial cells
| Diagnosis | Number | Percentage of positive cell (mean ± SD) | Incidence of positive cases (number positive/total number) |
|---|---|---|---|
| Control group |
40 |
2.4 ± 1.2 |
0 (0.0) |
| Study group |
151 |
|
|
| CIN I |
27 |
9.2 ± 4.6* |
44.4% (12 /27)* |
| CIN II/III |
54 |
16.0 ± 14.4* |
85.1% (46/54)* |
| Carcinoma in situ |
17 |
19.7 ± 13.3* |
88.3% (15 /17)* |
| Invasive Carcinoma |
28 |
47.0 ± 25.2 * |
100% (28 /28)* |
| CIN LEEP post-treatment |
11 |
7.2 ± 2.7* |
18.2% (2 /11) |
| Cervical cancer post-treatment | 14 | 7.1 ± 2.0* | 14.3% (2 /14) |
FISH, fluorescence in situ hybridization; hTERC, human telomerase mRNA component gene; Number, number of cases; CIN, cervical intraepithelial neoplasia; LEEP, loop electrical excision procedure. *P < 0.05 (compared with the control group).