Table 3.
Relationship between TCT diagnosis and hTERC amplification in exfoliated cervical epithelial cells
| TCT Diagnosis | Number | Percentage of positive cells (mean ± SD) | Incidence of positive cases (%) |
|---|---|---|---|
| Control group |
40 |
2.4 ± 1.2 |
0 (0.0) |
| Study group |
151 |
|
|
| NILM |
16 |
3.2 ± 2.1 |
0 (0.0) |
| ASCUS |
29 |
8.7 ± 6.3* |
13 (44.8)* |
| LSIL |
34 |
10.8 ± 4.8* |
23 (67.6)* |
| HSIL |
44 |
23.9 ± 15.0* |
41 (93.2)* |
| SCC | 28 | 31.07 ± 22.0* | 28 (100)* |
TCT, thinprep cytologic test; FISH, fluorescence in situ hybridization; hTERC, human telomerase mRNA component gene; Number, number of cases; NILM, negative for intraepithelial lesion or malignancy; ASCUS, atypical squamous cells of undetermined significance; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; SCC, squamous cell carcinoma. *P <0.05(compared to the control group).