Table 2.

Results of functional genomic analysis of major up-regulated gene expression sets in HVC (Figure 2C)

GO Term	GO Description	SD+CXT+LD7	LD21+LD56
GO:0000226	Microtubule cytoskeleton organization	p<0.005
GO:0060052	Neurofilament cytoskeleton organization	p<0.005
GO:0006096	Glycolysis	p<0.01
GO:0007264	Small GTPase mediated signal transduction	p<0.05
GO:0030131	Clathrin adaptor complex	p<0.05
GO:0000785	Chromatin		p<0.05
GO:0004707	MAP kinase activity		p<0.05

Gene ontology was used to determine significant functional categories that were associated with higher levels of gene expression in SD, CXT and LD7 compared to LD21 and LD56 starlings. Only significant values are shown (p < 0.05) for candidate terms, see Additional file 6: Table S6 for full list.