Table 4.
Effect of SAME on thyroid GSH, TBARS, H2O2, nitrite
| Treatment | GSH (μM/g tissue) | TBARS(nM /min/mg protein) | H2O2(nM/min/mg tissue) | Nitrite (μM/ml) |
|---|---|---|---|---|
| Control |
4.590±0.29++ |
9.66±.66++ |
6.5±0.48++ |
48.0±2.38++ |
| 3 ml/kg CCl4 |
2.82±0.06** |
19.02±0.44** |
11.3±1.05** |
62.0±2.14** |
| 100 mg/kg SAME+CCl4 |
4.06±0.19**++ |
14.33±0.49**++ |
10.0±0.36** |
52.8±2.85**++ |
| 200 mg/kg SAME+CCl4 |
4.50±0.20++ |
13.16±0.60**++ |
6.5±0.48++ |
44.2±2.06++ |
| 200 mg/kg SAME alone | 4.73±0.198++ | 11.33±0.76++ | 6.13±0.38++ | 41.3±2.09 ++ |
Mean ±SE (n=6 number).
** indicate significance from the control group at P<0.01 probability level.
++ indicate significance from the CCl4 group at P<0.01 probability level.