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. 2012 Oct 31;7(10):e48462. doi: 10.1371/journal.pone.0048462

Figure 4. AT1b receptor deficiency had no effect on AngII-induced abdominal aortic dilation in vivo.

Figure 4

(A) Maximal luminal diameters of suprarenal aortas were measured in vivo by ultrasonography at baseline (Day 0) and on Day 28 during AngII infusion (N = 16: AT1b receptor +/+, and N = 10: AT1b receptor −/− mice). * denotes P<0.001 saline versus AngII within AT1b genotypes (two way repeated measures ANOVA). (B) Maximum width of supra-renal aortas was measured ex vivo (N = 16: AT1b receptor +/+, and N = 10: AT1b receptor −/− mice). Inverted triangles represent individual mice, circles represent means and error bars are SEM. (C) Examples of ultrasound images (Day 0 and Day 28) and ex vivo pictures (after termination) of suprarenal aortas, which represent aortic diameters nearest the mean of each group.