Table 1. Comparison of baseline and echocardiographic characteristics between patients with appropriate and inappropriate left ventricular mass.
| Characteristics | All patients (n = 1110) | Appropriate LVM (n = 352) | Inappropriate LVM (n = 758) |
| Age (year) | 61.3±13.8 | 60.9±14.3 | 61.4±13.5 |
| Male gender (%) | 58.2 | 52.3 | 60.9* |
| Diabetes mellitus (%) | 29.1 | 23.9 | 31.5* |
| Hypertension (%) | 71.1 | 66.5 | 73.7* |
| Coronary artery disease (%) | 19.8 | 15.3 | 21.9* |
| PAD (%) | 15.7 | 9.4 | 18.6** |
| Mean arterial pressure (mmHg) | 97.2±14.0 | 99.7±13.0 | 96.0±14.3** |
| Pulse pressure (mmHg) | 58.6±14.6 | 61.2±14.3 | 57.4±14.5** |
| Body mass index (kg/m2) | 26.1±4.0 | 24.8±3.5 | 26.7±4.1** |
| Laboratory parameters | |||
| Albumin (g/dL) | 4.07±0.45 | 4.12±0.43 | 4.05±0.46 |
| Fasting glucose (mg/dL) | 114.2±41.5 | 112.7±41.2 | 115.0±41.6 |
| Triglyceride (mg/dL) | 124 (86–186) | 118 (83–171) | 128 (87–190.75)* |
| Total cholesterol (mg/dL) | 191.2±43.8 | 193.1±42.8 | 190.3±44.2 |
| Hematocrit (%) | 40.2±5.6 | 40.2±5.0 | 40.1±5.9 |
| Baseline eGFR (mL/min/1.73 m2) | 57.0±20.7 | 59.2±19.7 | 56.0±21.1* |
| eGFR <45 mL/min/1.73 m2 (%) | 23.7 | 19.3 | 25.7* |
| eGFR <60 mL/min/1.73 m2 (%) | 51.0 | 47.4 | 52.6 |
| Medications | |||
| ACEI and/or ARB use (%) | 56.8 | 46.1 | 61.5** |
| β-blocker use (%) | 43.5 | 38.0 | 46.0* |
| Calcium channel blocker use (%) | 36.8 | 33.0 | 38.6 |
| Diuretic use (%) | 28.8 | 16.5 | 34.5** |
| Echocardiographic data | |||
| Observed/predicted LVM (%) | 153.2±48.3 | 108.7±16.6 | 173.8±44.0** |
| LVEF (%) | 60.9±14.5 | 65.6±10.2 | 58.7±15.6** |
| LVRWT | 0.38±0.09 | 0.35±0.07 | 0.40±0.09** |
| E-wave deceleration time (ms) | 204.8±67.1 | 201.4±60.0 | 206.4±70.2 |
| E/A | 1.01±0.52 | 1.01±0.47 | 1.00±0.55 |
Abbreviations. LVM, left ventricular mass; PAD, peripheral artery disease; eGFR, estimated glomerular filtration rate; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; LVEF, left ventricular ejection fraction; LVRWT, left ventricular relative wall thickness; E, transmitral E wave velocity; A, transmitral A wave velocity.
*
P<0.05, **P<0.001 compared to patients with appropriate LVM.