Table 1. Definitions and interpretations of cerebral blood flow (CBF) map parameters.

Map parameter	Definition	Interpretation	Reference
Arrival time (Tarrival)	Initiation time of rise of the first passageafter bolus injection.	Tarrival reflects the fastest vascular path from the heart.Marked occlusion of major arteries will alter Tarrivalmaps. Absolute value of Tarrival is affected largely bythe bolus injection method.	[44]
Rising time (Trising)*	Time taken to reachthe first peak after arrival of bolus.	Trising may be a primary choice for evaluation of localtissue perfusion. Volume of blood supply isrepresented in Trising maps with a high contrast.	[26]
Mean transit time (MTT)	Mean detection time of ICGparticles in a region of interest.	MTT calculates whole blood supply including delayedcollateral flows. MTT may be a better choice in casesof low signal-to-noise ratios.	[27]
Blood flow index (BFI)*	The slope of the first peak ina time-intensity curve.	BFI represents overall blood volume informationwith respect to time.	[15], [33]

^*Other reports may use T_max and I_max instead of T_peak and I_peak, respectively.

t, observation time point; I(t), intensity function of time; I_peak, intensity of the first peak; T_peak, time of I_peak; I_arrival, intensity at T_arrival; I_max, maximum intensity; T_max, time of I_max.