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. 2012 Oct 31;7(10):e48415. doi: 10.1371/journal.pone.0048415

Table 1. The demographic and clinicopathological characteristics of glioma patients.

Variables Total(n = 270) n(%) HGG(n = 162) n(%)
Age (years)
<65 228(84.4) 126(77.8)
≥65 42(15.6) 36(22.2)
Gender
Male 177(62.1) 103(63.6)
Female 193(32.6) 59(36.4)
Primary/Secondary
PrimaryGlioma 239(88.5) 137(84.6)
SecondaryGlioma 31(11.5) 25(15.4)
Seizure
Yes 60(22.2) 25(36.4)
No 210(77.8) 137(63.6)
IICP
Yes 103(38.1) 71(43.8)
No 167(61.9) 91(56.2)
Cystic degeneration
Yes 60(22.2) 41(25.3)
No 210(77.8) 121(74.7)
Necrosis on MRI
Yes 36(13.3) 31(19.1)
No 234(86.7) 131(80.9)
MTD (cm)
<5 114(42.2) 65(40.1)
≥5 156(57.8) 97(59.9)
Resection degree
>98% 208(77.0) 120(74.1)
<98% 62(23.0) 42(25.9)
Tumor grade and pathological category
WHO Grade I 7(2.6)
Pilocyticastrocytoma 7
WHO Grade II 101(37.4)
Astrocytoma 67
Oligodendroglioma 27
Mixedoligo-astrocytoma 7
WHO Grade III 45(16.7) 45(27.8)
Anaplasticastrocytoma 33 33
Anaplasticoligodendroglioma 11 11
Astroblastoma 1 1
WHO Grade IV 117(43.3) 117(72.2)
GBM 116 116
Gliosarcoma 1 1
Radiotherapy
Yes 175(64.8) 116(71.6)
No 95(35.2) 46(28.4)
Chemotherapy
Yes 174(64.4) 117(69.9)
No 96(35.6) 45(30.1)
Lineage
Astrocytic 225(83.3) 151(93.2)
Oligodendroglial 45(16.7) 11(6.8)
MGMT methylation
103(38.1) 79(48.5)
+ 167(61.9) 83(51.2)
KPS
<70 88(32.6) 73(45.1)
≥70 182(67.4) 89(54.9)

Abbreviations: GBM, glioblastoma multiforme; HGG, high-grade glioma; IICP, increased intracranial pressure; MTD, mean tumor diameter.