Table 1. The demographic and clinicopathological characteristics of glioma patients.
Variables | Total(n = 270) n(%) | HGG(n = 162) n(%) | ||
Age (years) | ||||
<65 | 228(84.4) | 126(77.8) | ||
≥65 | 42(15.6) | 36(22.2) | ||
Gender | ||||
Male | 177(62.1) | 103(63.6) | ||
Female | 193(32.6) | 59(36.4) | ||
Primary/Secondary | ||||
PrimaryGlioma | 239(88.5) | 137(84.6) | ||
SecondaryGlioma | 31(11.5) | 25(15.4) | ||
Seizure | ||||
Yes | 60(22.2) | 25(36.4) | ||
No | 210(77.8) | 137(63.6) | ||
IICP | ||||
Yes | 103(38.1) | 71(43.8) | ||
No | 167(61.9) | 91(56.2) | ||
Cystic degeneration | ||||
Yes | 60(22.2) | 41(25.3) | ||
No | 210(77.8) | 121(74.7) | ||
Necrosis on MRI | ||||
Yes | 36(13.3) | 31(19.1) | ||
No | 234(86.7) | 131(80.9) | ||
MTD (cm) | ||||
<5 | 114(42.2) | 65(40.1) | ||
≥5 | 156(57.8) | 97(59.9) | ||
Resection degree | ||||
>98% | 208(77.0) | 120(74.1) | ||
<98% | 62(23.0) | 42(25.9) | ||
Tumor grade and pathological category | ||||
WHO Grade I | 7(2.6) | |||
Pilocyticastrocytoma | 7 | |||
WHO Grade II | 101(37.4) | |||
Astrocytoma | 67 | |||
Oligodendroglioma | 27 | |||
Mixedoligo-astrocytoma | 7 | |||
WHO Grade III | 45(16.7) | 45(27.8) | ||
Anaplasticastrocytoma | 33 | 33 | ||
Anaplasticoligodendroglioma | 11 | 11 | ||
Astroblastoma | 1 | 1 | ||
WHO Grade IV | 117(43.3) | 117(72.2) | ||
GBM | 116 | 116 | ||
Gliosarcoma | 1 | 1 | ||
Radiotherapy | ||||
Yes | 175(64.8) | 116(71.6) | ||
No | 95(35.2) | 46(28.4) | ||
Chemotherapy | ||||
Yes | 174(64.4) | 117(69.9) | ||
No | 96(35.6) | 45(30.1) | ||
Lineage | ||||
Astrocytic | 225(83.3) | 151(93.2) | ||
Oligodendroglial | 45(16.7) | 11(6.8) | ||
MGMT methylation | ||||
– | 103(38.1) | 79(48.5) | ||
+ | 167(61.9) | 83(51.2) | ||
KPS | ||||
<70 | 88(32.6) | 73(45.1) | ||
≥70 | 182(67.4) | 89(54.9) |
Abbreviations: GBM, glioblastoma multiforme; HGG, high-grade glioma; IICP, increased intracranial pressure; MTD, mean tumor diameter.