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. 2012 Oct 31;7(10):e48102. doi: 10.1371/journal.pone.0048102

Figure 5. Composition of PPARG bound cis-regulatory modules is conserved between human and mouse macrophages.

Figure 5

A) Overlap between PPARG/RXR and PU.1 ChIP-seq peaks. Significance of overlap was calculated using proportion test. B) PPARG/RXR ChIP-Seq enrichment at PPARG/RXR sites without and with PU.1 overlap. C) Proportion of PPARG/RXR binding sites in human and mouse macrophages that are co-occupied by PU.1. D) Venn-diagram depicting the numbers of species-specific and retained PU.1 binding sites in human and mouse macrophages.