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. 2012 Oct 31;7(10):e48543. doi: 10.1371/journal.pone.0048543

Figure 5. Clioquinol reduced the number of Ki67-labeled cells in the dentate gyrus.

Figure 5

Progenitor cell proliferation emerged in the dentate gyrus of rats. (A) Brains were harvested at 1 week after seizure and then brain sections were immunohistochemically stained with Ki67. Progenitor cell proliferation was significantly higher in seizure-induced rats than in the sham operated rats. Seizure-induced progenitor cell proliferation was reduced by CQ. Scale bar = 200 µm. (B) Bar graph represents number of Ki67-immunoreactive cell in the subgranular zone of DG (n = 8). Data are means ± SE. *P<0.05.