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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Dev Neurobiol. 2012 Jun;72(6):943–952. doi: 10.1002/dneu.22009

Figure 3.

Figure 3

Consistent running results in increased hippocampal neurogenesis. The number of BrdU+ cells (A) as well as the total number of new neurons (B) was significantly increased in runners as compared to controls (N=5-9 per group) . The number of type D cells in the suprapyramidal layer of the dentate gyrus (C) in the runners was greater than controls but it did not reach significance (N=9 per group). There was no difference in type C cells in the suprapyramidal layer of the dentate gyrus between the groups (N=9 per group) (D). Examples of photomicrographs of BrdU+/NeuN+ labeling of newborn neurons in controls (E) and runners (G). Photomicrographs displaying doublecortin (DCX) expressing immature neurons in the dentate gyrus of control (F) and running (H) mice. Arrows and labels indicate the type D and type C cells analyzed in this study. Scale bars = 50μm. Data represents the mean ± SEM. (*p<0.05; ^ represents a strong trend).