Table 3.
General factors affecting healing in chronic DFU >6 months
Healed No. (%) | Not healed No. (%) | p | |
---|---|---|---|
Mean age ± SD (years) | 54.8±10.4 | 58.5±8.3 | 0.053 |
Male: female ratio | 3 | 3.3 | 0.871 |
Mean duration of ulcer ± SD (months) | 18.5±12.4 | 28.9±21.2 | 0.002* |
Smoking | 13 (35) | 24 (65) | 0.000* |
HbA1c | |||
< 7% | 33 (86) | 5 (14) | 0.000* |
>7% | 32 (46) | 38 (54) | 0.000* |
Limb perfusion | |||
Grade 1 | 37 (80) | 9 (20) | 0.001* |
Grade 2 | 27 (47) | 31 (53) | 0.001* |
Grade 3 | 1 (25) | 3 (75) | 0.001* |
Type of ulcer | |||
Neuropathic | 30 (79) | 10 (21) | 0.002* |
Neuroschemic | 28 (41) | 40 (59) | 0.002* |
Alcohol consumption | 10 (76) | 3 (24) | 0.189 |
Duration of DM>20years | 29 (58) | 21 (42) | 0.445 |
Type of DM | |||
Type 1 | 10 (71) | 4 (29) | 0 .357 |
Type 2 | 55 (58) | 39 (42) | 0.357 |
Glycemic control | |||
Insulin | 60 (64) | 36 (36) | 0.226 |
OHD | 3 (33) | 6 (67) | 0.226 |
Diet | 1 (33) | 2 (67) | 0.226 |
Associated comorbidities | |||
Hypertension | 18 (72) | 7 (28) | 0.169 |
IHD | 3 (75) | 1 (25) | 0.537 |
Renal disease | 2 (33) | 4 (67) | 0.167 |
Eye impairment | 42 (61) | 27 (39) | 0.874 |
p <0.05.
HbA1C = Glycated hemoglobin A1C, DM = diabetes mellitus, OHD = oral hypoglycemic drugs, IHD = ischemic heart disease