Table 3.
Age-Related Eye Disease Study 2 (AREDS2) Participant Retinal Characteristics
| Retinal Characteristics | ||
|---|---|---|
| Drusen/Age-Related Macular Degeneration Status | ||
| Participants with at least large drusen or advanced AMD | ||
| Large Drusen both eyesa | 2484 (59.1) | |
| Advanced age-related macular degeneration in non-study eye, large drusen in study eyeb | 1360 (32.4) | |
| Large drusen, ungradable photo in fellow eye | 2 (0) | |
| Participants with less than large drusen in both eyes or in study eye | ||
| Less than large drusen in both eyes | 74 (1.8) | |
| Large drusen in one eye, less than large drusen fellow eyec | 160 (3.8) | |
| Advanced age-related macular degeneration in non-study eye, less than large drusen in study eye | 108 (2.6) | |
| Ineligible participants | ||
| Advanced age-related macular degeneration in both eyes | 15 (0.3) | |
| Total participants | 4203 | |
| Age-Related Macular Degeneration Status by patient using Age-Related Eye Disease Study (AREDS) Simple Scale Score | ||
| 0 | 10 (0.2) | |
| 1 | 62 (1.5) | |
| 2 | 632 (15.1) | |
| 3 | 1108 (26.5) | |
| 4 | 2374 (57.7) | |
| Total participants | 4186d | |
a
24 participants with questionable neovascularization (1 neovascular lesion out of the following potential lesions: serous detachment of the sensory retina, hemorrhage, retinal pigment epithelial detachment (non-drusenoid type), fibrous tissue, or hard exudate) in one eye and 2 participants with bilateral questionable neovascularization
b
15 participants with questionable neovascularization in one eye
c
3 participants with questionable neovascularization in one eye
d
Missing are: 15 participants with bilateral neovascular AMD and 2 with ungradable fundus photographs