Skip to main content
. 2012 Oct 22;2012:912041. doi: 10.1155/2012/912041

Table 1.

Effects of the aqueous extract of A. multiflora stem bark and diazepam in the open field test in mice.

Groups Dose (mg/kg) Number of line traversed Rearing time (s) Grooming time (s) Time spent at the center (s)
Control 35 ± 5.2 23.54 ± 5.14 87.54 ± 12.62 5.70 ± 1.36
AM 150 49.12 ± 2.24 29.25 ± 3.46 57.32 ± 13.17 41.22 ± 5.61*
AM 300 48.21 ± 3.56 35.42 ± 2.20* 34.20 ± 6.16** 56.50 ± 4.04*
Diazepam 1 5.40 ± 4.32*** 9.10 ± 3.10*** 10.70 ± 8.56*** 123.00 ± 18.120**

Mice activity was measured 30 min after the last chronic administration of the aqueous extract of A. multiflora or 30 min after the single dose of diazepam administration. Data are expressed as mean ± SEM of 6 animals. *P < 0.05, **P < 0.01, and **P < 0.001, compared to the vehicle-treated control group.