Table 1.
Groups | Dose (mg/kg) | Number of line traversed | Rearing time (s) | Grooming time (s) | Time spent at the center (s) |
---|---|---|---|---|---|
Control | — | 35 ± 5.2 | 23.54 ± 5.14 | 87.54 ± 12.62 | 5.70 ± 1.36 |
AM | 150 | 49.12 ± 2.24 | 29.25 ± 3.46 | 57.32 ± 13.17 | 41.22 ± 5.61* |
AM | 300 | 48.21 ± 3.56 | 35.42 ± 2.20* | 34.20 ± 6.16** | 56.50 ± 4.04* |
Diazepam | 1 | 5.40 ± 4.32*** | 9.10 ± 3.10*** | 10.70 ± 8.56*** | 123.00 ± 18.120** |
Mice activity was measured 30 min after the last chronic administration of the aqueous extract of A. multiflora or 30 min after the single dose of diazepam administration. Data are expressed as mean ± SEM of 6 animals. *P < 0.05, **P < 0.01, and **P < 0.001, compared to the vehicle-treated control group.