Table 2.
Effects of repeated administration of the aqueous extract of A. multiflora (i.p.) on the light-dark transition test with mice.
Groups | Dose (mg/kg) | Latency time (s) | Transition number | Time spent in light compartment (s) |
---|---|---|---|---|
Control | — | 116.2 ± 12.16 | 3.4 ± 0.73 | 38.60 ± 2.26 |
AM | 150 | 196.60 ± 8.90*** | 7.2 ± 0.86** | 53.80 ± 3.13* |
AM | 300 | 181.20 ± 11.20*** | 8.8 ± 0.86*** | 83.60 ± 4.06*** |
Diazepam | 1 | 57.40 ± 3.73*** | 15.40 ± 1.20*** | 105.00 ± 3.33*** |
Aqueous extract of A. multiflora stem bark was given (i.p) once per day for 7 days. Diazepam was given (i.p.) only once 30 min prior to the test. Data are expressed as means ± SEM. n = 6 animals per group. *P < 0.05; **P < 0.01; ***P < 0.001 versus control.