Table 1.

Regression analysis results comparing the frequency and rates of variant types per-individual genome across 10 global populations.

	Y-int	Africa			Europe		Asia		India	Mexico	R-Sqr
		LW	AS	MK	CE	TS	CH	JP	GI	ME
Total derived genotypes	6042271.00	−83419.25	−57488.00	−51149.25	−395516.33	−375283.25	−428364.00	−442378.00	−332701.50	−444921.80	0.97
Non-sense SNPs:	117.11	7.14	3.09	−4.86	−12.44	−11.61	−10.36	−12.11	−12.61	−5.11	0.45
Frameshift structural variants:	450.11	−7.86	−3.51	−15.36	−64.56	−36.11	−35.36	−37.61	−21.36	−55.11	0.71
Splicing change variants:	3009.33	−17.08	17.47	9.42	4.33	14.92	−34.08	−48.58	−5.08	2.07	0.29
Probably damaging nscSNPs:	2842.67	15.83	9.13	−42.92	−197.89	−168.92	−198.67	−213.17	−177.42	−208.67	0.90
Possibly damaging nscSNPs:	2201.44	17.31	11.56	−13.19	−148.00	−120.94	−150.19	−139.69	−143.19	−133.84	0.82
Protein motif damaging variants:	1012.22	−16.72	−21.02	−17.72	−111.44	−82.22	−89.47	−109.72	−69.47	−108.22	0.76
TFBS disrupting variants:	625.67	−92.67	−65.67	−39.42	−122.56	−117.67	−74.17	−80.67	−56.42	−155.67	0.75
miRNA-BS disrupting variants:	215.78	−7.28	−10.78	−15.78	−51.00	−42.53	−49.78	−51.78	−41.03	−66.58	0.91
ESE-BS disrupting variants:	2912.00	−33.25	−6.80	−35.75	−141.89	−138.50	−187.75	−163.25	−134.25	−140.00	0.82
ESS-BS disrupting variants:	1225.56	−17.31	−1.36	15.19	−43.56	−40.31	−54.06	−71.56	−40.31	−84.56	0.72
Total likely functional variants:	12983.11	−148.11	−71.31	−133.11	−730.11	−599.61	−729.61	−734.86	−557.86	−783.11	0.90
Functional variants/total variants × 100000	214.87	0.53	0.86	−0.38	2.12	3.65	3.40	3.86	2.75	3.09	0.57
Total number of novel variants:	230608.44	19681.56	−16356.84	−26810.44	−133947.00	−122674.44	−110435.44	−113591.94	−98801.19	−125688.44	0.92
Total likely functional novel variants:	798.78	66.22	−22.18	−125.03	−360.56	−290.78	−251.03	−263.78	−250.03	−331.78	0.84
Total number of homozygous genotypes:	2919451.44	2748.06	680.16	30050.56	371821.44	362882.06	429429.81	426953.06	331099.31	377807.36	0.99
Probably damaging hmz nscSNPs:	985.00	0.75	−20.80	25.75	202.78	191.00	243.75	191.75	160.00	207.60	0.97
Prob Dam hmz nscSNPs/Total Var iants × 100000	16.30	0.24	−0.19	0.57	4.73	4.45	5.58	4.71	3.75	5.00	0.98
Total likely functional homozygous variants:	6103.11	30.39	−19.71	62.14	772.00	762.39	907.39	877.89	606.14	835.09	0.98
Likely functional hmz variants/total Variants × 100000	101.02	1.91	0.64	1.89	20.74	20.14	23.86	23.65	16.49	22.94	0.99

Note that the YR (Yoruban) sample was taken as the reference. Y-int = Y-intercept; R-Sqr = Fraction of Variation in the Variant type explained by the regression model. Bolded entries = p-value < 0.05; Italicized entries = p-value <  0.0005.