Table 3.

Frequency and rates (×10000) of population-specific variant types for African (AFR), European (EUR), and Asian (ASN) populations.

Variant type	Populations			z-test p-values
	AFR	EUR	ASN	AFR vs. EUR AFR vs. ASN EUR vs. ASN
Total number of variants:		7614850	2024886	1294731
Non-sense SNPs rate	0.500	0.840	0.842	6.931E-09	6.329E-07	4.910E-01
Frameshift structural variants rate	1.663	3.008	2.989	1.597E-34	6.239E-25	4.621E-01
Frameshift insertion rate	0.657	1.274	1.383	6.368E-19	1.089E-18	2.006E-01
Frameshift deletion rate	0.879	1.417	1.352	3.877E-12	1.584E-07	3.102E-01
Frameshift rearrangement rate	0.127	0.316	0.255	2.614E-09	2.228E-04	1.572E-01
Splicing change variants rate	1.707	2.514	2.379	4.655E-14	7.112E-08	2.223E-01
Probably damaging nscSNPs rate	10.103	15.472	15.602	1.136E-91	4.578E-69	3.853E-01
Possibly damaging nscSNPs rate	5.991	7.744	8.233	7.313E-19	3.064E-21	6.111E-02
Protein motif damaging variants rate	4.104	6.311	6.581	2.612E-39	3.043E-35	1.726E-01
TFBS disrupting variants rate	2.793	4.173	4.063	7.493E-69	2.764E-42	1.785E-01
miRNA-BS disrupting variants rate	0.948	1.170	1.081	2.405E-03	7.715E-02	2.286E-01
ESE-BS disrupting variants rate	5.835	7.260	7.283	1.696E-13	2.840E-10	4.689E-01
ESS-BS disrupting variants rate	2.460	3.013	2.865	6.435E-06	3.539E-03	2.232E-01
Total likely functional variant rate	23.718	34.906	35.436	8.999E-170	1.234E-132	2.128E-01