Table 2.
Distribution of TRAF polymorphisms (rs3761847 and rs2900180) in patients with primary biliary cirrhosis (PBC) and controls.
| SNP | Allele/genotype | PBC (%) (n = 179) | Controls (%) (n = 300) | χ 2 | P (Fisher exact) | OR |
|---|---|---|---|---|---|---|
| rs3761847 | A/G | 210/148 | 356/244 | 0.07 | 0.84 | 1.04 [0.79–1.35] |
| AA | 64 (35.8) | 99 (33) | 0.38 | 0.55 | 1.13 [0.77–1.67] | |
| AG | 82 (45.8) | 158 (52.7) | 2.12 | 0.16 | 0.76 [0.52–1.10] | |
| GG | 33 (18.4) | 43 (14.3) | 1.41 | 0.25 | 1.35 [0.82–2.22] | |
|
| ||||||
| rs2900180 | C/T | 114/244 | 185/415 | 0.13 | 0.72 | 1.05 [0.79–1.39] |
| CC | 84 (46.9) | 144(48) | 0.052 | 0.85 | 0.96 [0.66–1.39] | |
| CT | 76 (42.5) | 127 (42.3) | 0.001 | >0.99 | 1.02 [0.70–1.49] | |
| TT | 19 (10.6) | 29 (9.7) | 0.11 | 0.75 | 1.11 [0.60–2.04] | |