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. 2012 Nov 15;72(10):839–847. doi: 10.1016/j.biopsych.2012.05.027

Table 2.

Mediation Analyses Results with BAS as the Outcome Variable

Region Path a Path b Path c' Path c Path a*b
Amygdala
 Path coefficient .39 9.24 −4.28 −.67 3.62
 STE .40 4.13 5.68 6.24 4.31
 p .32 .04 .22 .70 .25
Caudate
 Path coefficient .87 9.13 −8.41 −.66 7.74
 STE .52 3.64 5.74 6.23 5.49
 p .01 .01 .04 .70 .02
Nucleus Accumbens
 Path coefficient .84 8.73 −7.98 −.67 7.31
 STE .50 3.50 6.05 6.15 5.55
 p .01 .02 .07 .71 .01
Putamen
 Path coefficient .69 10.98 −7.89 −.65 7.23
 STE .41 4.75 5.84 6.22 4.71
 p .005 .02 .06 .71 .01

Results from mediation analyses where fetal testosterone is the predictor, mean Happy > Fear region of interest response is the mediator, and total behavioral approach system (BAS) score summing across all subscales is the outcome variable. Path a is the relationship between the predictor and the mediator. Path b is the relationship between the mediator and the outcome, controlling for the predictor. Path c' is the relationship between the predictor and the outcome controlling for the mediator. Path c is the total effect of the relationship between the predictor and the outcome, irrespective of the mediator. Path a*b is the difference between path c and path c'. Hypothesis testing and statistical significance was evaluated with bootstrapping. An effect was statistically significant if the value 0 was not within the 95% bias-corrected and accelerated bootstrap confidence intervals.

STE, standard error.