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Subcellular expression of P-AKT, by immunohistochemistry, in thyroid tumors from PTEN mutation-positive CS/CSL patients
| P-AKT staining |
||||
|---|---|---|---|---|
| Negative | Nuclear | Cytoplasmic | Nuclear and cytoplasmic | |
| n (%) | 5 (22.7) | 10 (45.5) | 3 (13.6) | 4 (18.2) |
| Atypical FA (W/ thyroiditis) (n = 5) | 0 | 2 | 0 | 3 |
| Atypical FA (W/O thyroiditis) (n = 7) | 3 | 4 | 0 | 0 |
| Follicular Ca. (n = 3) | 0 | 1 | 1 | 1 |
| Papillary Ca. (n = 5) | 2 | 2 | 1 | 0 |
| Anaplastic Ca. (n = 2) | 0 | 1 | 1 | 0 |
FA, Follicular adenoma; Ca., carcinoma; W, with; W/O, without.
