Table 1.
Clinical characteristics and biochemical markers of premenopausal (PRE) and postmenopausal (POST) women and all women combined
| All (n = 23) | PRE (n = 10) | POST (n = 13) | P value | |
|---|---|---|---|---|
| Variables | ||||
| Age (yr) | 55.1 (29.3–60.1) | 28.8 (24.3–31.0) | 57.3 (55.4–62.8) | <0.001 |
| Height (cm) | 1.66 (1.62–1.73) | 1.72 (1.62–1.74) | 1.65 (1.62–1.70) | 0.306 |
| Weight (kg) | 66.9 (62.1–72.3) | 70.1 (62.1–73.3) | 66.0 (62.4–70.0) | 0.438 |
| BMI (kg/m2) | 24.2 (22.4–25.5) | 24.7 (22.9–25.0) | 23.8 (22.4–26.0) | 0.926 |
| Sympathetic activity (bursts per 100 heart beats) | 48.9 (29.5–64.1) | 24.8 (11.1–34.3) | 59.1 (50.4–68.1) | <0.001 |
| Bone turnover markers | ||||
| PINP (μg/liter) | 49.5 (36.9–81.6) | 39.7 (35.0–82.7) | 52.0 (44.8–77.1) | 0.556 |
| CTX (ng/ml) | 0.46 (0.33–0.69) | 0.34 (0.29–0.47) | 0.55 (0.36–0.69) | 0.182 |
| Regulatory markers | ||||
| OPN (ng/ml) | 67.9 (58.9–80.7) | 64.8 (59.0–73.5) | 73.8 (58.2–84.4) | 0.556 |
| Total sRANKL (pmol/liter) | 844 (183–7330) | 539 (220–7330) | 1562 (100–5866) | 0.975 |
| OPG (pmol/liter) | 4.4 (3.2–5.4) | 3.4 (2.8–5.8) | 4.6 (3.9–5.4) | 0.278 |
| Sclerostin (pmol/liter) | 32.3 (24.9–40.1) | 26.6 (14.2–29.0) | 36.7 (34.8–40.5) | 0.006 |
| Total 25(OH)D (ng/ml) | 36.0 (31.0–43.0) | 34.5 (30.0–42.0) | 39.0 (34.0–43.0) | 0.514 |
Data are shown as median (IQR).