Skip to main content
. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Ann N Y Acad Sci. 2008 Apr;1126:194–200. doi: 10.1196/annals.1433.064

FIGURE 1.

FIGURE 1

Effects of hSVCT2 overexpression in mouse lens epithelial and fiber cells on uptake and lenticular levels of vitamin C and dehydroascorbic acid (DHA). (A) Immunohistochemical staining of a typical control (left) and transgenic (right) lens with an antibody against the C-terminal portion of hSVCT2 reveals a diffuse presence of hSVCT2 along the cell membrane in cortical layers of the lens. (B) ASA concentration in 16 lenses from hSVCT2 mice, 13 controls from the same litter, and six human lenses. (C) DHA concentration in 10 lenses from hSVCT2 and control mice. WT = wild type; TG = transgenic.