Table 4.
Centromeric and telomeric haplotypesa associated with KIR2DL5
| Haplo | No. Individuals | 2DL2 2DL3 | 2DL5B | 2DS3 2DS5 | Haplo | No. Individuals | 3DS1 | 2DL5A | 2DS3 2DS5 | 2DS1 |
|---|---|---|---|---|---|---|---|---|---|---|
| C1 | 14 | 2*00101 | *0020101/03 | 3*00103 | T1 | 9 | *01301 | *0010101 | 5*00201 | *00201 |
| C2 | 1 | 2*00101 | *0020101/03 | 3*00105 | T2 | 1 | *01301 | *0010101 | 5*00201 | *006 |
| C3 | 1 | 2*00101 | *0020101/03 | 3*004 | T3 | 1 | *049N | *0010101 | 5*00201 | *00201 |
| C4 | 1 | 2*00102 | *0020101/03 | 3*00103 | T4 | 1 | *01301 | *00102 | 5*00201 | *00201 |
| C5 | 1 | 2*00101 | *0020104 | 3*00103 | T5 | 2 | *01301 | *0050101 | 3*002 | *00201 |
| C6 | 1 | 2*00101 | *0020106 | 3*00103 | T6 | 1 | *01301 | *01201 | 5*009 | *00201 |
| C7 | 1 | 3*014 | *0020106 | 3*00103 | T7 | 1 | *01301 | *01202 | 5*006 | - |
| C8b | 1 | 2*00301 | *00202 | 3*00106 | ||||||
| C9 | 1 | 2*004 | *003 | 5*003 | ||||||
| C10 | 3 | 2*00101 | *004 | 5*006 | ||||||
| C11 | 7 | 2*00602 | *00601 | 5*007 | ||||||
| C12 | 2 | 2*00301 | *00601 | 5*009 | ||||||
| C13 | 1 | 2*00301 | *00601 | 5*00201 | ||||||
| C14 | 1 | 2*00601 | *00601 | 5*009 | ||||||
| C15 | 3 | 2*00602 | *00603 | 5*006 | ||||||
| C16 | 1 | 3*014 | *0070102 | 5*003 | ||||||
| C17 | 1 | 2*00101 | *0080101 | 5*00201 | ||||||
| C18 | 1 | 2*00101 | *0080101 | 5*007 | ||||||
| C19 | 1a | 2*007 | *0080101 | 5*007 | ||||||
| C20 | 1 | 2*00301 | *0080102 | 5*009 | ||||||
| C21 | 1 | 2*00601 | *010 | 3*00104 | ||||||
| C22 | 1 | 2*00101 | *01301 | 5*005 | ||||||
| C23 | 1 | 2*00101 | *01302 | 5*00801 |
Each haplotype was identified by the physical linkage of adjacent loci in all individuals carrying the haplotype. The exceptions were KIR2DS1 which was not physically linked to adjacent loci in all individuals carrying a particular haplotype and haplotypes C20 (linkage of KIR2DL2) and haplotype C8 which were predicted based on common associations. It is not known whether the gene segments carried in the centromeric gene complex are located on the same chromosome as the telomeric gene complex in individuals who carry both. The number of individuals carrying the haplotype are listed in the table; the table does not include two KIR2DL5 positive individuals in whom haplotypes could not be determined by physical linkage or be predicted. This included the individual carrying novel allele KIR2DL5*01303.