Table 2.

Effects of natural polyphenols on neutrophils.

Compound		References
Resveratrol	↓superoxide anion, ↓hypochlorous acid, ↓chemotaxis ↓5-LOX, ↓myeloperoxidase, ↓ROS formation ↓expression ICAM-1, VCAM-1, MAC-1, β2-integrin ↓activity protein kinases (MAPK, JNK) ↓elastase, ↓β-glucuronidase, ↓chemotaxis, ↓NO production	Perečko et al., 2008; Alarcón de la Lastra & Villegas, 2005; Cavallaro et al., 2003; Adams et al., 2005; Kohnen et al., 2007
Pterostilbene	↓ROS formation	Perečko et al., 2008; Perečko et al., 2010
Pinosylvin	↓5-LOX, ↓ROS formation	Perečko et al., 2008; Adams et al., 2005
Piceatannol	↓Syk, ↓phagocytosis and adhesion, ↑apoptosis, ↓TNFα, ↓PGE2,↓IL-8, ↓ROS production, ↓p40phox phosphorylation	Ennaciri & Girard, 2009; Richard et al., 2005; Jančinová et al., 2011a
Curcumin	↓aggregation, ↓ROS production, ↑apoptosis, ↓chemotaxis, ↓protein kinase C activation, ↓5-LOX	Srivastava et al., 2011; Jančinová et al., 2009; Jančinová et al., 2011; Prasad et al., 2004
N-feruloyl serotonin	↓ROS production, ↓protein kinase C activation	Nosáľ et al., 2011; Nosáľ et al., 2010

Abbreviations used: see Table 1.