Skip to main content
. 2012 Oct;167(4):768–777. doi: 10.1111/j.1365-2133.2012.11040.x

Table 3.

Summary of associations between HLA-DRB1 alleles and pemphigus vulgaris

HLA-DRB1 type Studies
Allele counts

Heterogeneity
Model
Association
Sensitivity analysis
Publication bias
Patients (n events/n total) Controls (n events/n total) χ2 Ph I2% Pc OR 95% CI Funnel plot Begg’s test (Pr) Egger’s test (P)
*01 9,10,12,13,15,28,31,33,34 27/730 166/2330 6·91 0·55 0 Fixed 0·002 0·50 0·33–0·77 None S 0·902 0·795
*03 9,10,12,15,27,28,3134 35/988 299/2690 8·65 0·47 0 Fixed < 0·00001 0·28 0·19–0·41 None S 0·602 0·604
*04 9,10,12,13,15,27,28,3034 366/1150 697/5397 66·31 < 0·00001 83 Random < 0·00001 3·61 2·28–5·71 None S 0·537 0·645
*07 9,10,12,27,28,31,3335 55/962 289/2436 19·34 0·01 59 Random 0·004 0·45 0·26–0·78 None S 0·754 0·864
*08 10,12,15,28,31,32,34 43/630 49/2724 12·94 0·04 54 Random 0·03 2·25 1·07–4·70 Except15,31,32 S 1·000 0·873
*09 10,28,33,34 21/378 102/1200 2·70 0·44 0 Fixed 0·07 0·59 0·34–1·04 None S 0·734 0·670
*10 10,12,15,28,33,34 6/538 44/1482 2·49 0·78 0 Fixed 0·09 0·48 0·21–1·12 None S 0·296 0·512
*11 10,12,15,28,31,33,34 75/604 347/2000 2·51 0·87 0 Fixed < 0·00001 0·47 0·34–0·63 None S 0·764 0·814
*12 10,12,15,28,33,34 19/538 71/1952 14·25 0·01 65 Random 0·83 0·88 0·27–2·83 None S 1·000 0·668
*13 10,12,15,28,31,33,34 35/566 129/1504 2·51 0·87 0 Fixed 0·06 0·68 0·45–1·01 Except12,34 S 1·000 0·654
*14 10,12,13,15,27,28,3134 336/1048 199/3280 24·40 0·004 63 Random < 0·00001 6·47 4·52–9·26 None A 0·049 0·034
*15 10,15,27,28,31,34 35/736 216/1594 10·43 0·06 52 Random 0·001 0·35 0·18–0·66 None S 1·000 0·533
*16 10,15,28,34 9/402 56/1254 1·56 0·67 0 Fixed 0·05 0·47 0·23–0·98 Except15,28,34 S 1·000 0·773

Ph, P-value for heterogeneity; Pc, P-value for comparability; OR, pooled odds ratio; CI, confidence interval; S, symmetrical; A, asymmetrical.