. 2012 Oct;167(4):768–777. doi: 10.1111/j.1365-2133.2012.11040.x

Table 4.

Summary of associations between HLA-DRB1 phenotypes and pemphigus vulgaris

HLA-DRB1 type	Studies	Patients (n events/n total)	Controls (n events/n total)	Heterogeneity							Model	Association
χ²	Ph	I²%	Pc	OR	95% CI	Funnel plot	Begg’s test (Pr)	Egger’s test (P)
^*01	¹⁴^,¹⁶^,¹⁷^,²⁹^,³¹^,³⁵	17/145	91/571	22·73	0·0004	78	Random	0·70	0·75	0·17–3·34	Except¹⁷	S	0·452	0·174
^*03	¹⁶^,¹⁷^,²⁹^,³¹^,³²^,³⁵	8/145	333/1332	6·80	0·24	27	Fixed	0·0001	0·25	0·12–0·51	None	S	0·734	0·619
^*04	⁸^,¹⁴^,¹⁶^,¹⁷^,²⁹^,³¹^,³²^,³⁵	116/213	360/1902	32·42	< 0·00001	78	Random	0·0002	4·14	1·98–8·65	None	S	0·711	0·894
^*07	¹⁶^,¹⁷^,²⁹^,³¹^,³²^,³⁵	9/129	255/1036	6·06	0·30	17	Fixed	0·0002	0·27	0·14–0·54	None	S	1·000	0·837
^*08	⁸^,¹⁴^,¹⁶^,¹⁷^,²⁹^,³¹^,³²^,³⁵	33/181	83/1096	5·18	0·52	0	Fixed	0·0003	2·46	1·51–4·01	None	S	0·707	0·896
^*09	⁸^,¹⁴^,¹⁶^,¹⁷^,³⁵	4/134	196/983	1·18	0·88	0	Fixed	0·0003	0·19	0·08–0·46	None	S	1·000	–
^*10	¹⁶^,¹⁷^,³⁵	4/66	16/413	3·25	0·20	39	Fixed	0·25	1·85	0·65–5·23	None	S	–	–
^*11	¹⁶^,¹⁷^,²⁹^,³¹^,³⁵	27/113	145/526	3·42	0·49	0	Fixed	0·13	0·68	0·41–1·12	Except¹⁶	S	0·734	0·595
^*12	¹⁴^,¹⁶^,¹⁷^,³⁵	2/98	24/458	1·19	0·76	0	Fixed	0·39	0·59	0·17–1·97	None	A	–	–
^*13	¹⁴^,¹⁶^,¹⁷^,²⁹^,³¹^,³⁵	13/145	125/571	6·85	0·23	27	Fixed	0·005	0·42	0·23–0·77	Except¹⁶	S	0·308	0·123
^*14	⁸^,¹⁴^,¹⁶^,¹⁷^,²⁹^,³¹^,³²^,³⁵	118/213	179/1902	24·86	0·0008	72	Random	< 0·00001	9·68	4·47–20·98	None	A	0·368	0·548
^*15	¹⁴^,¹⁷^,²⁹^,³¹^,³⁵	9/119	73/371	6·12	0·19	35	Fixed	0·002	0·32	0·16–0·65	Except¹⁴	S	0·221	0·014
^*16	¹⁷^,²⁹^,³⁵	3/73	35/315	4·20	0·12	52	Random	0·55	0·55	0·08–3·96	None	S	–	–

Ph, P-value for heterogeneity; Pc, P-value for comparability; OR, pooled odds ratio; CI, confidence interval; S, symmetrical; A, asymmetrical.