Table 5.
Meta-analysis stratified by study quality and ethnicity
| HLA–DRB1 type |
Ethnicity |
Quality |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
Asian |
Caucasian |
Other |
High |
Low |
||||||
| I2% | 95% CI | I2% | 95% CI | I2% | 95% CI | I2% | 95% CI | I2% | 95% CI | |
| *04 genotype | 0 | 1·33–3·86 | 87 | 1·65–7·71 | 84 | 1·62–7·05 | 88 | 1·78–6·96 | 76 | 1·97–7·18 |
| *04 phenotype | 89 | 0·65–3·79 | 46 | 2·39–4·40 | – | 1·49–3·32 | 82 | 1·84–4·09 | 62 | 0·78–2·73 |
| *07 genotype | 75 | 0·16–4·22 | 16 | 0·19–0·57 | 13 | 0·29–0·92 | 68 | 0·21–0·50 | 0 | 0·37–0·93 |
| *08 genotype | – | 0·36–2·43 | 0 | 2·38–9·68 | 0 | 0·60–2·74 | 60 | 0·97–4·67 | – | 0·30–126·18 |
| *14 genotype | 53 | 3·00–15·13 | 56 | 4·71–13·10 | 7 | 3·37–6·81 | 66 | 5·91–9·78 | 45 | 3·54–7·88 |
| *14 phenotype | 86 | 0·79–124·32 | 46 | 4·68–19·39 | – | 1·68–14·02 | 76 | 3·25–23·68 | 77 | 2·08–59·37 |
| *15 genotype | 65 | 0·05–1·92 | 58 | 0·16–1·11 | 0 | 0·10–0·43 | 53 | 0·19–0·99 | 0 | 0·18–0·66 |
CI, confidence interval. Significant results are shown in bold. –, only one study involved.