Fig 4.

The humoral response to B. burgdorferi proteins varies between DBA/1 and C3H/HeJ mice. ELISA plates coated with B. burgdorferi cell lysate were probed with DBA/1 and C3H/HeJ infected mouse sera (n = 10 per strain) and secondary antibodies specific for murine class- and isotype-specific antibodies. Antibody densities were compared for each class and isotype as indicated. No differences were found between total IgG-IgM (A), IgG (B), IgM (C), or IgG1 (D) levels. IgG2a density (E) was significantly decreased in DBA/1 versus C3H/HeJ mice (P < 0.05). Mean values are depicted with standard errors.