Table 3.
Demographics and vaccination frequencies
| Parametera | Result for vaccine and dose (IU) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HVTN 040 |
HVTN 059 |
|||||||||
| Placebo (n = 8) | 1 × 104 (n = 20) | 1 × 105 (n = 20) | Total (n = 48) | Placebo (n = 14) | 1 × 105 (n = 20) | 1 × 106 (n = 20) | 1 × 107 (n = 20) | 1 × 108 (n = 10) | Total (n = 84) | |
| Sex | ||||||||||
| Male | 4 (50%) | 12 (60%) | 9 (45%) | 25 (52%) | 9 (64%) | 10 (50%) | 13 (65%) | 10 (50%) | 5 (50%) | 47 (56%) |
| Female | 4 (50%) | 8 (40%) | 11 (55%) | 23 (48%) | 5 (36%) | 10 (50%) | 7 (35%) | 10 (50%) | 5 (50%) | 37 (44%) |
| Race | ||||||||||
| White non-Hispanic | 4 (50%) | 7 (35%) | 5 (25%) | 16 (33%) | 3 (21%) | 10 (50%) | 5 (25%) | 9 (45%) | 4 (40%) | 31 (37%) |
| Black/African American non-Hispanic | 3 (38%) | 12 (60%) | 14 (70%) | 29 (60%) | 8 (57%) | 10 (50%) | 14 (70%) | 11 (55%) | 3 (30%) | 46 (55%) |
| Hispanic | 1 (13%) | 1 (5%) | 0 (0%) | 2 (4%) | 2 (14%) | 0 (0%) | 0 (0%) | 0 (0%) | 3 (30%) | 5 (6%) |
| Native Hawaiian/Pacific Islander or multiracialb | 0 (0%) | 0 (0%) | 1 (5%) | 1 (2%) | 1 (7%) | 0 (0%) | 1 (5%) | 0 (0%) | 0 (0%) | 2 (2%) |
| Age (yr) | ||||||||||
| 18–20 | 1 (13%) | 0 (0%) | 1 (5%) | 2 (4%) | 1 (7%) | 2 (10%) | 0 (0%) | 2 (10%) | 0 (0%) | 5 (6%) |
| 21–30 | 2 (25%) | 9 (45%) | 13 (65%) | 24 (50%) | 9 (64%) | 10 (50%) | 10 (50%) | 8 (40%) | 4 (40%) | 41 (49%) |
| 31–40 | 1 (13%) | 3 (15%) | 2 (10%) | 6 (13%) | 3 (21%) | 3 (15%) | 4 (20%) | 5 (25%) | 2 (20%) | 17 (20%) |
| 41–50 | 2 (25%) | 7 (35%) | 4 (20%) | 13 (27%) | 1 (7%) | 5 (25%) | 6 (30%) | 5 (25%) | 4 (40%) | 21 (25%) |
| Over 50 | 2 (25%) | 1 (5%) | 0 (0%) | 3 (6%) | ||||||
| Median | 39.5 | 32.0 | 27.0 | 29.5 | 25.5 | 26.5 | 30.5 | 29.5 | 32.0 | 28.5 |
| Range | 20–55 | 21–54 | 20–48 | 20–55 | 20–48 | 20–48 | 21–50 | 18–45 | 24–46 | 18–50 |
| Vaccination frequencies | ||||||||||
| Day 0 | 8 (100%) | 20 (100%) | 20 (100%) | 48 (100%) | 14 (100%) | 20 (100%) | 20 (100%) | 20 (100%) | 10 (100%) | 84 (100%) |
| Day 28 | 8 (100%) | 19 (95%) | 18 (90%) | 45 (94%) | 11 (79%) | 20 (100%) | 19 (95%) | 12 (60%) | 10 (100%) | 72 (86%) |
| Day 84 | 8 (100%) | 18 (90%) | 17 (85%) | 43 (90%) | 10 (71%) | 20 (100%) | 17 (85%) | 10 (50%) | 9 (90%) | 66 (79%) |
a
Results are no. (%) unless otherwise noted.
b
Data represent Native Hawaiian/Pacific Islander subjects for HVTN 040 and multiracial subjects for HVTN 059.