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. 2012 Oct;11(10):1289–1299. doi: 10.1128/EC.00215-12

Table 6.

Genes downregulated by at least 1.5-fold in strains carrying UPC2 GOF alleles

Functiona CGD name orf19 designation Change in expression (fold)b in indicated experiment
G648S
G648D
Y642F
A643V
1 2 1 2 1 2 1 2
Transport HGT10 orf19.5753 0.6 0.5 0.2 0.2 0.5 0.6 0.2 0.3
Pathogenesis SAP7 orf19.756 0.4 0.4 0.3 0.2 0.4 0.4 0.3 0.4
Biological activity unknown orf19.716 0.4 0.5 0.4 0.4 0.6 0.6 0.4 0.4
orf19.3621 0.3 0.5 0.3 0.3 0.6 0.4 0.5 0.5
orf19.4873 0.4 0.5 0.6 0.5 0.6 0.6 0.6 0.6
a

Descriptions of genes are from the Candida Genome Database (http://www.candidagenome.org).

b

Fold change is defined as the average ratio of gene expression levels in the isolates compared in two independent microarray experiments.

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