Table 1.
List of TLO genes in SC5314 and important features
| Namea | Phylogenetic nameb | Alternate splicingc | Length (aa)d | Functional motif(s) (aa)e | NLSf |
|---|---|---|---|---|---|
| TLO1 | TLOα1 | No | 258 | Med2 (1–109) | Yes |
| TLO2 | TLOβ2 | No | 273 | Med2 (1–119), EF-hand (196–208) | Yes |
| TLO3 | TLOα3 | No | 255 | Med2 (1–115) | Yes |
| TLO34 | TLOα34 | No | 331 | Med2 (75–183) | Yes |
| TLO4 | TLOψ4 | No | NAg | NA | NA |
| TLOγ4 | No | 140 | Med2 (1–104) | No | |
| TLO5 | TLOγ5 | Yes | 176 | Med2 (1–108) | No, yes |
| TLO7 | TLOγ7 | ? | 169, 206 | Med2 (1–107) | No |
| TLO8 | TLOγ8 | ? | 169 | Med2 (1–108) | No |
| TLO9 | TLOα9 | No | 225 | Med2 (1–108) | Yes |
| TLO10 | TLOα10 | No | 219 | Med2 (1–108) | Yes |
| TLO11 | TLOγ11 | ? | 169 | Med2 (1–108) | No |
| TLO12 | TLOα12 | No | 252 | Med2 (1–108) | Yes |
| TLO13 | TLOγ13 | Yes | 176, 213 | Med2 (1–108) | No, yes |
| TLO16 | TLOγ16 | Yes | 179, 184 | Med2 (1–108) | No |
a
Based on the work of van het Hoog et al. (44).
b
Based on this study.
c
Based on RT-PCR analysis (Fig. 1).
d
Predicted protein length (unspliced, spliced).
e
Predicted functional motifs with Pfam/Prosite scores above P < 1 × 10−5.
f
Presence of predicted NLS based on PredictNLS with score above P < 1 × 10−5 (unspliced, spliced).
g
NA, not applicable.