Fig 2.

Bafilomycin production in the ksbC disruptant. The amount of bafilomycin was the total amount of bafilomycin derivatives (bafilomycin A1, B1, and C1). Error bars represent standard deviations from triplicate experiments. WT, wild-type strain; ΔksbC/−, ksbC disruptant; ΔksbC/pSET152, ΔksbC strain carrying pSET152; ΔksbC/ksbC, ksbC-complemented ΔksbC strain; WT/pSET152, the wild-type strain carrying pSET152. (A) Effect of ksbC disruption on bafilomycin production. (B) Complementation of the ksbC disruptant and effect of the pSET152 integration into the genome of K. setae on bafilomycin production.