Table 2.

Chronic effects of blood flow restricted training on vascular function and related biomarkers.

Author & year	Subjects	Age (yrs)	Applied cuff pressure (mmHg)	Intensity or time	Reps, sets, or time	Exercise modality	Intervention period	Occlusion time (min)	Cuff width (cm)	Outcome	Effect
Credeur et al. (2010) [140]	5 men 7 women	22	80	60% 1 RM	15 reps/min, 20 min	HG	3 days/wk 3 wk	20	?	FMD	−
Hunt et al. (2012) [141]	9 men	26	80	40% 1 RM	20 reps/min until exhaustion	HG	3 days/wk 4 wk	8.5	13	FMD Diameter	~ +
Clark et al. (2011) [128]	8 men 1 women	24	SBP ∗ 1.3	30% 1 RM	8–12 reps/set, Total 30–50 reps	KE	3 days/wk 3 wk	?	6	PWV, ABI D-dimer, PT Fibrinogen	~,~ ~,~ ~
Fahs et al. (2012) [129]	10 men	21	160–200	20% 1 RM	30 reps +15 reps ∗ 3 set	KE, KF	3 days/wk 6 wk	12	5	Arterial compliance Vascular conductance	~ ~
Kim et al. (2009) [127]	10 men	18–35	SBP ∗ 1.2 ∗ 1.2	20% 1 RM	10 reps ∗ 2	KE, KF, LP	3 days/wk 3 wk	<15	5	Arterial compliance	~
Ozaki et al. (2011) [134]	3 men 10 women	66	140–200	45% HRR	20 min	walking	4 days/wk 10 wk	20	5	Arterial compliance	+
Ozaki et al. (2012) [130]	10 men	22–32	160	30% 1 RM	30 reps + 15 reps ∗ 3 set	BeP	3 days/wk 6 wk	?	3	Arterial compliance	~
Patterson and Ferguson (2010) [119]	8 men 8 women	23 22	110	25%, 50% 1 RM	20 reps/min ∗ 3 sets	PF	3 days/wk 4 wk	5–8	?	Post-occlusive blood flow	+
Evans et al. (2010) [138]	9 men	20	150	Own BW	50 reps ∗ 4	CR	3 days/wk 4 wk	?	?	Microvascular filtration capacity	+

SBP: systolic blood pressure; HRR: heart rate reserve; BW: body weight; HG: hand grip; PF: planter flexion; CR: calf raise; BeP: Bench press; PWV: pulse wave velocity; ABI: ankle-brachial blood pressure index. PT: prothrombin time; +: positive effect; −: negative effect; ~: no effect.