Table 2.
Data among HCV-positive patients who underwent hepatectomy for HCC carrying GG, GA, and AA allele at rs1012068 (DEPDC5).
| rs1012068 | TT (n = 50) | TG/GG (n = 14) | P value |
|---|---|---|---|
| Age (y), mean ± SD | 69 ±1 | 71 ± 2 | n.s |
| Sex (male/female), n | 38/12 | 12/2 | n.s |
| Platelet count (×104/μL), mean ± SD | 13.5 ± 0.8 | 15.1 ± 1.5 | n.s |
| Total bilirubin level (mg/dL), mean ± SD | 0.9 ± 0.07 | 0.9 ± 0.1 | n.s |
| Prothrombin time (%), mean ± SD | 0/11/10 | 0/1/7 | n.s |
| ICGR15 (%), mean ± SD | 16.5 ± 1.4 | 15.7 ± 2.2 | n.s |
| Operative time (min), mean ± SD | 344 ± 15 | 357 ± 29 | n.s |
| Intraoperative bleeding (mL), mean ± SD | 631 ± 75 | 817 ± 146 | n.s |
| Maximum tumor size (cm), mean ± SD | 3.4 ± 0.5 | 4.0 ± 0.6 | n.s |
| AFP level (ng/mL), mean (minimum–maximum) | 2004 (2.0–5846) | 250 (5.5–17156) | n.s |
| DCP level (mAU/mL), mean (minimum–maximum) | 2429 (10–46561) | 1348 (9–15526) | n.s |
| Stage (I/II/III/IV), n | 7/28/14/1 | 3/8/3/0 | n.s |
| Tumor differentiation (well/moderate /poorly), n | 11/35/4 | 3/8/3 | n.s |
| Fibrosis stage (F0-2/F3-4), n | 19/31 | 8/6 | <0.05 |
AFP: alpha-fetoprotein, DCP: des-gamma-carboxy prothrombin, HCC: hepatocellular carcinoma, ICGR15: indocyanin green retention at 15 minutes, and n.s: not significant.