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. 2012 Oct 24;2012:580696. doi: 10.1155/2012/580696

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Copyright © 2012 Li-Chiu Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Anti-CD4 antibody treatment efficiently reduced CD4⁺ T cells in the spleen of wild-type mice. (a) The percentages of CD4⁺ T cells and CD19⁺ B cells in the spleens of wild-type mice treated with control antibody (− CD4 depletion) or anti-CD4 antibody (+ CD4 depletion) 7 days postinfection analyzed by flow cytometry are shown. CD4^−/− mice serve as a control for the assay. (b) The average percentages of CD4⁺ T cells and CD19⁺ B cells in spleens of the indicated mouse groups are shown. The data shown are the mean values plus SE values (error bars) of 3 spleens.